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Fighting for a new era of cancer care

With over 2 decades of scientific innovation across oncology, Pfizer continues to drive the next wave of cancer breakthroughs. Approximately 40% of all our research and development investment is directed toward oncology.

We're dedicated to developing therapies in 5 key cancer types, including breast, genitourinary, hematologic, thoracic, and gastrointestinal cancers. This work spans 3 core modalities to attack cancer from multiple angles: small molecules, antibody-drug conjugates (ADCs), and immuno-oncology biologics, including bispecific antibodies.

Attacking cancer from multiple angles

Our research spans three main modalities where we have significant depth, world-class capabilities, and expertise.


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Antibody-drug conjugates

Antibody-drug conjugates bind to cancer cell proteins to deliver cytotoxic drugs directly to tumors.

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Bispecifics

Bispecifics grab both the intended target cancer cell and an immune cell, bringing them close enough together for the immune cell to destroy the cancer cell.

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Small molecules

Small molecules get inside cancer cells and disrupt their growth and progression. With a legacy of transforming treatment for certain cancers, we are researching novel small molecule medicines that have the potential to overcome treatment resistance and other challenges.

Learn more about biomarker testing

Stay current with the latest oncology biomarker information and guidelines.

Explore cancer biomarkers

Looking into the future with 50+ programs in development1

We are working to develop new potential standards of care in some of the world's most common cancers, including breast, gastrointestinal, genitourinary, hematologic malignancies, and thoracic.

See the full pipeline



Learn about our 90+ oncology clinical trials worldwide1

Our clinical trials span nearly 4,000 study sites around the globe.

Search Pfizer clinical trials

Visit Clinicaltrials.gov

Real-world evidence

Conducting real-world data (RWD) analyses to generate real-world evidence (RWE) is a growing practice in the healthcare community. RWE provides helpful information that can complement clinical trial findings and may help fill knowledge gaps related to how a medication is used in real-world medical settings.

These studies can include de-identified patient-related data collected from various sources, including but not limited to, anonymized electronic medical records, claims databases, health surveys, and patient registries. The insights gleaned from these analyses may inform a greater understanding of a medicine’s real-world effectiveness, safety, and cost.



See how we support the cancer community

Pfizer seeks to meet the needs of the oncology community through advocacy partnerships, disease education, health literacy initiatives, and access/affordability programs.

Supporting your patients with key resources

Explore a range of resources—from helpful downloads to connecting with patient groups—that support patients on their journey.

References:

  1. Fighting for a new era of cancer care. Accessed April 24, 2026. https://cancer.pfizer.com/hcp
  2. Data on file. Pfizer Inc., New York, NY.