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Biomarker testing can make a difference

Testing for biomarkers can shed light on how a patient's cancer will likely behave, help identify potential clinical trial options, and support informed decision-making with your patients.1

As a busy healthcare provider, you may not always have time to research relevant biomarker information for each case. So use the information below to help you find what you need quickly and easily.

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Explore biomarker resources with ease

Download a handy reference of biomarkers from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®)

Refer to this guide for information on biomarkers and their respective testing options across the most common solid tumor types.

Download PDF

Use this tool to review biomarker information for specific tumor types

Bladder cancer biomarkers1

Biomarkers
Testing option(s)
PD-L1
55%

FGFR3=fibroblast growth factor receptor 3, HER2=human epidermal growth factor receptor 2, IHC=immunohistochemistry.

NCCN makes no warranties of any kind whatsoever regarding their content, use or application and disclaims any responsibility for their application or use in anyway.

Last updated on April 28, 2026.

Reference:

  1. Referenced with permission from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Bladder Cancer v2.2026. © National Comprehensive Cancer Network, Inc. 2026. All rights reserved. Accessed April 28, 2026. To view the most recent and complete version of the guideline, go online to NCCN.org.

Download biomarker PDF now

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Help your patients understand biomarkers

Learn more

Stay on top of the latest NCCN Guidelines®

Explore NCCN Guidelines new NCCN Guidelines Navigator™

Access this interactive digital tool to easily search and navigate the NCCN Guidelines2

Learn more

Subscribe to NCCN Guidelines NCCN Flash Updates™

You'll get updates on a range of NCCN Guidelines resources sent directly to your inbox.3

Learn more

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Biomarker testing allows for guided therapy that can prevent unnecessary treatments and costs

77% of patients who have had biomarker testing agree that it gave their providers valuable information on how to treat the patient's cancer*4
~60% of oncology drugs brought to market in the US in the past five years require or recommend biomarker testing prior to use5
23% of patients who have had biomarker testing say that it led to changes in their treatment plan, with 3% saying it helped them enroll in a clinical trial*4

*Based on a survey of 1,222 respondents.6

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With biomarkers, knowledge is power

Biomarker testing looks different for every cancer, so knowing which steps to take is important. Visit the sites below to see some ways Pfizer is raising awareness about individual biomarkers and how to test for them.

Visit ActFastBRAF.com

Visit HRRmTesting.com

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Help your patients get the answers they need

Our customizable discussion guide creator helps patients have more focused conversations about biomarkers with their healthcare team.

Visit PfizerForAll.com

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References:

  1. This is living with cancer: biomarker testing in cancer treatment. Accessed April 28, 2026. https://www.thisislivingwithcancer.com/understanding-cancer/genetic-testing
  2. NCCN guidelines navigator. Accessed April 28, 2026. https://www.nccn.org/guidelines/nccn-guidelines-navigator
  3. NCCN flash updates. Accessed April 28, 2026. https://www.nccn.org/business-policy/business/flash-updates
  4. Cancer patients and survivors overwhelmingly agree biomarker testing improved Their Treatment. Accessed April 28, 2026. https://www.fightcancer.org/policy-resources/cancer-patients-and-survivors-overwhelmingly-agree-biomarker-testing-improved-their
  5. Increasing access to biomarker testing. Accessed April 28, 2026 https://www.fightcancer.org/increasing-access-biomarker-testing-0
  6. Survivor views: biomarker testing September 2023. Accessed April 28, 2026. https://www.fightcancer.org/sites/default/files/national_documents/survivorviews_biomarkers.pdf
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